A-01 Registration Tuesday 14:00-18:00 |
A-02 Opening ceremony and welcome reception Tuesday 18:00-20:00 |
A-03 Registration Wednesday 08:00-08:40 |
A-04 Welcome and introduction Wednesday 08:40-08:55 |
A-05 Alexander Staab In Memoriam Hans Schaefer Wednesday 08:55-09:00 |
A-06 Joachim Grevel Panel Discussion: Modelling and Simulation and the Regulatory Process Wednesday 09:00-10:15 |
A-07 Coffee break, poster and software session I: posters in Group I (with poster numbers starting with I-) are accompanied by their presenter Wednesday 10:15-11:45 |
A-08 Bruno Bieth Model-based analyses for pivotal decisions, with an application to equivalence testing for biosimilars Wednesday 11:45-12:05 |
A-09 Sylvain Goutelle A unified in vivo modeling approach for quantitative prediction of the impact of gene polymorphism and drug interactions on drug exposure Wednesday 12:05-12:25 |
A-10 France Mentré Launch of the new journal 'CPT: Pharmacometrics & Systems Pharmacology' Wednesday 12:25-12:30 |
A-11 Nick Holford The International Society of Pharmacometrics Wednesday 12:30-12:35 |
A-12 Kyungsoo Park The World Conference on Pharmacometrics (WCoP) Wednesday 12:35-12:40 |
A-13 Lunch Wednesday 12:40-14:05 |
A-15 Jakob Ribbing Literature Model for FEV1 in COPD Trials – Separating the Dynamic Components of Placebo Effect, Disease Progression and Interacting Drug Effects Wednesday 14:55-15:15 |
A-16 Tea break, poster and software session II: posters in Group II (with poster numbers starting with II-) are accompanied by their presenter Wednesday 15:15-16:45 |
A-17 Thomas Eissing A physiologically-based PK/PD model to capture population variability for diabetes research and automatic blood glucose control Wednesday 16:45-17:05 |
A-18 Maria Kjellsson Predicting late-phase outcome from early-phase findings using a Model-Based Approach – Application to Type 2 Diabetes Mellitus Wednesday 17:05-17:25 |
A-19 Franziska Schädeli Stark Semi-physiologic population PKPD model characterizing the effect of bitopertin (RG1678) glycine reuptake inhibitor on hemoglobin turnover in humans Wednesday 17:25-17:45 |
A-20 James Yates Applying mechanistic pharmacokinetic-pharmacodynamic models (PKPD) to describe the growth and inhibition of xenograft tumours in rats and mice by targeted anti-cancer agents. Thursday 08:45-09:05 |
A-21 Ben-Fillippo Krippendorff Relationship between the dose of therapeutic antibodies and the inhibition of cytoplasmic and nuclear growth factor signalling Thursday 09:05-09:25 |
A-22 Mélanie Wilbaux Population K-PD joint modeling of tumor size and CA 125 kinetics after chemotherapy in relapsed ovarian cancer (ROC) patients Thursday 09:25-09:45 |
A-23 Ekaterina Gibiansky PK/PD modeling and optimization of eltrombopag dose and regimen for treatment of chemotherapy-induced thrombocytopenia (CIT) in cancer patients Thursday 09:45-10:05 |
A-24 Coffee break, poster and software session III: posters in Group III (with poster numbers starting with III-) are accompanied by their presenter Thursday 10:05-11:35 |
A-25 Thomas Dorlo Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive cover after use of miltefosine for the treatment of visceral leishmaniasis Thursday 11:35-12:00 |
A-26 Sebastian Ueckert Application of Item Response Theory to ADAS-cog Scores Modelling in Alzheimer’s Disease Thursday 12:00-12:25 |
A-27 Presentation of Lewis Sheiner student session awards Thursday 12:25-12:30 |
A-28 Lunch Thursday 12:30-14:00 |
A-29 Mats Karlsson Introduction to Markov modelling Thursday 14:00-14:40 |
A-30 Oliver Ackaert A hidden Markov model to assess drug-induced sleep fragmentation Thursday 14:40-15:00 |
A-31 Tea break, poster and software session IV: posters in Group IV (with poster numbers starting with IV-) are accompanied by their presenter Thursday 15:00-16:30 |
A-32 Chee Ng Novel Hybrid Artificial Neural Network-Nonlinear Mixed Effect Model Modeling Approach for Population Data Analysis in Model-based Drug Development Thursday 16:30-16:50 |
A-33 William Denney N-dimensional Likelihood Profiling: An Efficient Alternative to Bootstrap Thursday 16:50-17:10 |
A-34 Gilbert Koch Modeling of delayed phenomena in PKPD by delay differential equations of lifespan type Thursday 17:10-17:30 |
A-35 Social event Thursday 20:00 |
A-36 Aris Dokoumetzidis Lumping of compartments Friday 09:00-09:35 |
A-37 Jin Jin Model-Based Meta-Analysis for the Efficacy and Safety of Paclitaxel in Cancer Patients Friday 09:35-09:55 |
A-38 Yasunori Aoki A practical algorithm for practical parameter identifiability analysis Friday 09:55-10:15 |
A-39 Preview of PAGE2013 Friday 10:15-10:25 |
A-40 Coffee break Friday 10:25-10:55 |
A-41 Anne-Gaelle Dosne A strategy for residual error modeling incorporating both scedasticity of variance and distribution shape Friday 10:55-11:15 |
A-42 Ron Keizer Extended NPDE diagnostics for the between-subject variability and residual error model Friday 11:15-11:35 |
A-43 Camille Vong Handling Below Limit of Quantification Data in Optimal Trial Design Friday 11:35-11:55 |
A-44 France Mentré Survey on the current use of optimal design approaches and the developments needed in adaptive optimal design for model based analysis performed amongst DDMoRe’s EFPIA members Friday 11:55-12:15 |
A-45 Closing remarks Friday 12:15-12:25 |
A-46 Audience input for potential PAGE2013 topics Friday 12:25-12:40 |